Bone Marrow Banking
What We Make
Bone marrow, or medulla ossium, is the spongy material found in the center of bones. Bone marrow is composed of haematopoietic cells, stromal cells, and adipose tissue. It is the primary site of haematopoiesis, or blood formation, in humans. Ossium uses stem cell science to make cell therapies from bone marrow that are being evaluated as treatments for hematologic diseases, organ rejection, and diseases of inflammation.
Diseases of the blood and immune systems like leukemia, lymphoma, myeloma, and sickle cell disease claim roughly 60,000 lives each year in the US alone. Many of these lives could be saved with cell therapies, but too often patients are unable to get access to these treatments. Ossium is building a vast and diverse bank of deceased-donor bone marrow to make these life-saving treatments available to patients worldwide.
Organ Transplant Rejection
Today’s organ transplants are lifesaving treatments for organ failure, but they are not cures. The lifelong regimen of immunosuppressive drugs needed after transplant causes chronic infections and poor quality of life. At Ossium, we’re developing stem cell therapies that could enable organ transplant recipients to live healthy lives without immunosuppression by re-educating their immune systems to recognize cells from their organ donors as self.
Diseases of Inflammation
The mesenchymal stem cells (MSCs) present in vertebral bone and marrow have the capacity to regulate immune and inflammatory responses, providing a promising option for the treatment of diseases characterized by inflammation. Ossium is working to develop MSC-based therapies that are intended to help patients with a vast array of inflammatory and autoimmune disorders such as Crohn’s Disease, asthma, and graft-versus-host disease.