Bone Marrow Banking


What We Make

Bone marrow, or medulla ossium, is the spongy material found in the center of bones. Bone marrow is composed of haematopoietic cells, stromal cells, and adipose tissue. It is the primary site of haematopoiesis, or blood formation, in humans. Ossium uses stem cell science to make cell therapies from bone marrow that are being evaluated as treatments for hematologic diseases, organ rejection, and diseases of inflammation.


The Process


How It Works

1


Recover donor tissue using aseptic recovery protocols.

2


Process bone marrow from donor tissue in state-of-the-art cleanrooms.

3


Cool bone marrow to temperatures below the threshold for biological activity to preserve cells for decades.

4


Distribute cell therapies to healthcare providers for the treatment of patients in need.


Applications


Hematologic Diseases

Diseases of the blood and immune systems like leukemia, lymphoma, myeloma, and sickle cell disease claim roughly 60,000 lives each year in the US alone. Many of these lives could be saved with cell therapies, but too often patients are unable to get access to these treatments. Ossium is building a vast and diverse bank of deceased-donor bone marrow to make these life-saving treatments available to patients worldwide.


Organ Transplant Rejection

Today’s organ transplants are lifesaving treatments for organ failure, but they are not cures. The lifelong regimen of immunosuppressive drugs needed after transplant causes chronic infections and poor quality of life. At Ossium, we’re developing stem cell therapies that could enable organ transplant recipients to live healthy lives without immunosuppression by re-educating their immune systems to recognize cells from their organ donors as self.


Diseases of Inflammation

The mesenchymal stem cells (MSCs) present in vertebral bone and marrow have the capacity to regulate immune and inflammatory responses, providing a promising option for the treatment of diseases characterized by inflammation. Ossium is working to develop MSC-based therapies that are intended to help patients with a vast array of inflammatory and autoimmune disorders such as Crohn’s Disease, asthma, and graft-versus-host disease.


Products

HPC, Marrow

Selected CD34+ Cells

Mesenchymal Stem Cells (MSCs)


Partners


Working with Ossium

Ossium works closely with healthcare providers, life science companies, and organ procurement organizations to develop and deploy cell therapies.

Healthcare Providers

Life Science Companies

Organ Procurement Organizations

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